Around twelve Saturday afternoon, crews were called to a two-story home on Glass Mill Road which is just off US 27 in Nicholasville.
When firefighters arrived on scene, the home was fully engulfed.
Investigators say, no one was inside the home at the time of the fire. There were two pets inside home during the fire, but they were able to get out unharmed.
Officials plan to investigate the scene to to and find out what started the fire.